Must / Should / Have to / It is essential that

Article excerpt · target grammar marked

When a shipment of active pharmaceutical ingredient arrives at a facility, QA technicians must verify its identity, purity, and particle size before a single gram enters production.

Grammar Reference · Must / Should / Have to / It is essential that

must — internal

Used for rules the speaker or organisation sets. QA teams must document every deviation immediately.

have to — external

Used for obligations from outside (law, regulator). Manufacturers have to follow FDA Good Manufacturing Practice guidelines.

should —

Strong advice; not compulsory but best practice. Batch records should be reviewed within 24 hours of completion.

it is essential that

Formal written register; used in SOPs and reports. It is essential that all entries be signed by an authorised person.

01Exercise 1 — Form · Write the Correct Form

Must / Should / Have to / It is essential that

1.All incoming raw materials be tested for identity and purity before use.

2.Manufacturers in the EU comply with European Medicines Agency GMP standards.

3.It is essential that the batch record completed before the shift ends.

4.QA managers inform the production team of any batch hold within one hour.

5.Facilities submit their annual product quality review to the regulator every year.

6.In-process tablet weight checks run every 30 minutes during production.

02Exercise 2 — Find and Correct the Error

find the error · rewrite the sentence

1.Manufacturers should to follow GMP guidelines at all times.

2.It is essential that the record is sign before the batch is released.

3.QA teams must to document every deviation the same day.

4.Facilities have follow FDA rules when they export to the US market.

5.It is essential that all temperature data logged every 60 seconds.

6.Inspectors should to check batch records for missing signatures.

7.The production manager must reviews the deviation report before 5 p.m.

8.It is essential that the clean room humidity are monitored continuously.

03Exercise 3 — About You

in your notebook

Personalise: complete five sentences about yourself using the target grammar.

Must / Should / Have to / It is essential that01classplan.ai